Signal Transduction Reagents and Kits
Cell Biolabs Inc ViraDuctin™ Retrovirus Transduction Kit, 40 transductions
The rate at which retroviral vectors bind to and infect cells is mostly controlled by diffusion. During retrovirus infection, only a small fraction of the retroviral vectors can transduce target cells. Virion adsorption is the limiting step of this process. The use of polycations, such as Polybrene, is standard in many retroviral infection protocols owing to the observations of improved infection efficiency. Its mechanism of action is thought to involve neutralization of electrostatic repulsion between virion and cell membranes, enhancing attachment. ViraDuctin™ Retrovirus Transduction Kit is a proprietary formulation for the transduction of retrovirus. After forming a complex with retrovirus in culture medium, the ViraDuctin™ reagents typically provide higher transduction efficiency in many cell types compared to reagents such as Polybrene. It is ideal for transduction of nonpermissive cells such as primary cells and stem cells. 40 transductions.
Waters Corporation Upgrade Kit, Transducer BGM, for HPLC Systems
This upgrade kit is designed to update early 2545 Binary Gradient Modules in HPLC systems. It provides a newer style pressure transducer with a die-cast housing, along with tubing assemblies and an adapter, to replace older, round version transducers.
- Provides one pressure transducer and tubing assemblies.
- Updates early 2545 Binary Gradient Modules.
- Features a newer style transducer with a die-cast housing.
- Replaces older, round version transducers.
- Includes an adapter for installation to the pump head.
- Suitable for HPLC systems.
- Units per package: 1.
Creative Biomart Galsulfase, Human N-acetylgalactosamine 4-sulfatase
The product is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. The product is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular recognition. Post-translational modification of Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and is conserved in all members of the sulfatase enzyme family.
Medchemexpress LLC Syk-IN-1 | 14911150-77-6 | 99.2% | 10 MG
Syk-IN-1 is a potent Syk inhibitor, with an IC50 of 35 nM. This compound is provided as a light yellow to yellow solid and is intended for research use only.
- Potent Syk inhibitor with an IC50 of 35 nM.
- Molecular weight: 366.42.
- Molecular formula: C18H22N8O.
- Appearance: solid.
- Color: light yellow to yellow.
- In vitro solubility: DMSO (100 mg/mL).
- For research use only.
Medchemexpress LLC UK122 TFA | 940290-58-4 | 99.85% | 405.33 | 100 MG
UK122 TFA is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. It exhibits minimal or no inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50 >100 μM). This 4-oxazolidinone analogue acts as an anticancer agent that hinders cancer cell migration and invasion. This product is intended for research use only.
- Potent and selective uPA inhibitor
- Inhibits cancer cell migration and invasion
- Minimal inhibition of tPA, plasmin, thrombin, and trypsin
- Suitable for in vitro studies
Enzo Life Sciences D609 (5 mg). CAS: 83373-60-8
Selective inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC). Has been used to study the coupling of phosphatidylcholine-specific phospholipase C with sphingomyelinase. Shows antitumor and antiviral activity. Inhibits basement membrane collagen synthesis, which is the last step in the development of a new blood vessel. Inhibits induction of nitric oxide synthases (NOS). Induces apoptosis. It indirectly inhibits phorbol ester stimulated PLD activity. Alternative name: Tricyclodecan-9-yl xanthogenate . K. Purity: ≥98% (TLC). Solubility: Soluble in water (25mg/ml). Long Term Storage: -20°C.